AgroScience Today, Volume 4, Issue 1 : 0543-0553
POPULAR ARTICLES

OPEN ACCESS | Published on : 31-Jan-2023

Antibiotics use in Livestock and its Linkages to Poisoned Food Cycle: Current Status and Way Forward

  • Katyayini Sharma
  • Shere Kashmir University of Agriculture & Technology, Jammu, India

Abstract

 The phrase "antibiotics" refers to a broad category of chemical compounds produced naturally, semi-synthetically, and artificially, and used to prevent (bacteriostatic) or eradicate bacterial development (bactericidal). They are divided into two categories: narrow- and broad-spectrum antibiotics, depending on whether they have bactericidal or bacteriostatic properties. Additionally, the tetracyclines, aminoglycosides β-lactams, lincosamides, macrolides, pleuromutilins, and sulphonamides are among the classes of antibiotics that are more commonly used in agriculture globally and that are the subject of growing scientific concern with regard to their possible side effects and risk management strategies. As the years advance, the use of antibiotics is increasing at a rapid pace. The antibiotics are not only used for humans but for food animals too to promote growth and prevent infection. This improper use of antibiotics has an influence on the selection of microorganisms that are resistant to them. These bacteria, which are antibiotic-resistant, are spread from food animals to humans, milk, meat, soil, and water. The author reviews the extent of antibiotic worldwide and the mechanism by which the microorganisms develop resistant against the antibiotics. The spread of antibacterial resistant bacteria and mechanism of gene transfer from one bacteria to other has also been discussed. Preventive measures that can be taken to reduce the antibiotic use in food animals and reduce the antibiotic resistance in the mere future have also been highlighted. 

Keywords

Antibiotic, livestock, feed-efficiency

References

  • Boxall, ABA, Fogg LA, Blackwell PA, Kay P, Pemberton EJ and CroxfordA (2004) Veterinary medicines in the environment. Rev. Enviro. ContamToxicol 180:1–91.

    Enne, VI, Delsol A A, Davis GR, Hayward SL, Roe JM, and Bennett PM (2005) Assessment of the fi tness impacts on Escherichia coli of acquisition of antibiotic resistance genes encoded by different types of genetic element. J AntimicroChemother56:544–551.

    FeinmenSE(1998)Antibiotics in animal feed: drug resistance revisited. AmSocMicrobiolNews 64:24-30.

    Finley RL, Collignon P, JoakimLarsson DG, McEwen SA, Xian-Zhi L, Gaze WH, Reid-Smith R, Timinouni M, Graham DW, Topp E(2013) The Scourge of Antibiotic Resistance: The Important Role of the Environment. Clin Infect. Dis. :57:704–710. doi: 10.1093/cid/cit355. 

    George G, (1998) Agricultural use of antibiotics and the evolution and transfer of antibiotic-resistant bacteria. Canadian Med. Assoc. J 159:1129-36.

    Hayden D, Hedman Karla A, Vasco Lixin Zhang(2020) A Review of Antimicrobial Resistance in Poultry Farming within Low-Resource Settings. Libretexts. Bacterial Transformation.4.1.

    Joanne C, Chee-Sanford,Roderick I, Mackie and Satoshi Koike.van G. Krapac.Yu-Feng Lin, Anthony C(2009) Transport of Antibiotic Residues and Antibiotic Resistance Genes following Land Application of Manure Waste. J Environ Qual 38:1086–1108

    KapoorGarimaand SaigalSaurabh(2017) Ashok Elongavan. Action and resistance mechanisms of antibiotics: A guide for clinicians.pp116.

    Magiorakos A, Srinivasan A, Carey RB, Carmeli Y, Falagas ME, GiskeCG(2012) Multidrug-resistant, extensively drug-resistant and pandrug-resistant bacteria: an internatiojnal expert proposal for interim standard definitions for acquired resistance. ClinMicrobiol Infect 18(3):268–81.

    Manyi-LoChristy h, MamphweliS ampson, Meyer Edson and Okoh (2018) Antibiotic Use in Agriculture and Its Consequential Resistance in Environmental Sources: Potential Public Health Implications. Published online Mar 30.  doi: 10.3390/molecules23040795

    Mathew G Alan 1, IsselRobin C, LiamthongS(2007) Antibiotic resistance in bacteria associated with food animals: a United States perspective of livestock production. Summer 4(2):115-33. doi: 10.1089/fpd.2006.0066.

     Milic N, Milanovic M, Letic NG, Sekulic MT, Radonic J, Mihajlovic I, Miloradov V(2013) Occurrence of antibiotics as emerging contaminant substances in the aquatic environment. Int. J Environ Health Res 23:296–310.

    Timothy F Landers, Bevin Cohen, Thomas EWittum and Elaine L Larson(2018) A Review of Antibiotic Use in Food Animals: Perspective, Policy, and Potential . Molecules : 23(4): 795.

    Xi C, Zhang Y, Marrs CF, Ye W, Simon C, Foxman B, Nriagu J(2009)Prevalence of antibiotic resistance in drinking water treatment and distribution systems.Appl.Environ .Microbiol. : 75(17):5714-8.