Nitroplast is a recently discovered eukaryotic organelle that functions in nitrogen-fixation. The first report of nitroplast was from the marine algae Braarudosphaera bigelowii, in which the endosymbiotic relationship of a nitrogen-fixing cyanobacteria evolved into an organelle. Like other organelles, during the course of evolution, the genome of the endosymbiotic organism lost many important genes and hence it cannot exist independently. As the B. bigelowii genome encodes most of the proteins required for the nitroplast, it is now regarded as an organelle. Engineering nitroplast enables autotrophic nitrogen fixation in crop plants, which in turn reduces the usage of chemical fertilizers, thereby leading to sustainable agricultural practices.
Nitroplast, organelle, endosymbiont, sustainable agriculture
Johnston, I.G. (2024). The Nitroplast and Its Relatives Support a Universal Model of Features Predicting Gene Retention in Endosymbiont and Organelle Genomes. Genome Biology and Evolution, 16, 7.
Liu, F., Fernie, A.R., Youjun Zhang,Y. (2024). Can a nitrogen-fixing organelle be engineered within plants?. Trends in Plant Science, 29 (11): 1168-1171
Masclaux-Daubresse, C., Daniel-Vedele, F., Dechorgnat, J., Chardon, F., Gaufichon, L., & Suzuki, A. (2010). Nitrogen uptake, assimilation and remobilization in plants: challenges for sustainable and productive agriculture. Annals of Botany, 105(7), 1141–1157.
Massana, R. (2024). The nitroplast: A nitrogen-fixing organelle. Science 384,160-161
Quemada, M., Delgado, A., Mateos, L., & Villalobos, F.J. (2024). Nitrogen Fertilization I: The Nitrogen Balance. In: Villalobos, F.J., Fereres, E. (eds) Principles of Agronomy for Sustainable Agriculture. Springer
Rong W, Lin L, Wang G. (2024). Nitroplasts suggest the creation of artificial nitrogen-fixing eukaryotes. Trends in Biotechnology. 42(8):946-948.
Samuels, F. (2025). The first known nitroplasts. Chemical & Engineering News. American Chemical Society
Ye, D., & Tsang, S.C.E. (2023). Prospects and challenges of green ammonia synthesis. Nature Synthesis. 2, 612–623.